Nexus of Gut Microbiota, AI, 3d Bioprinting, Pathogens: Gut-Brain Axis, Epidemiology Global, India, Code to Living Tissue, Inflammatory Bowel, Crohn's Disease, Ulcerative Colitis, Colorectal Cancer

Abstract

In humans, the microbiota in the gut interacts with the host and the gut-brain axis to maintain the health of the gastrointestinal tract, metabolism, immunity, and brain processes. Inflammatory bowel illnesses (IBDs) include Crohn's disease and ulcerative colitis (UC) as well as colorectal cancer (CRC) are strongly correlated with microbial dysbiosis. The subject of microbiome research has been greatly impacted by recent advancements in artificial intelligence and 3D printing. These technologies hold great promise for better illness prognosis, biomarker identification, personalized diagnosis, and the modelling of tissues particular to individual patients. This paper explores the relationship of gut microbiota, pathogens, AI and 3D bioprinting with a particular emphasis on the epidemiology of IBD and colorectal cancer (CRC) on the global and Indian scales. The results of the research showed that microbial dysbiosis can cause many diseases through immune dysregulation, inflammation, and gut-brain axis disturbance. Machine learning-based analytics and human-derived organoids and 3D bio printed tissues appear to be extremely useful in developing precision medicine and translational gastroenterology.